Mario Castro Selected Research

Respiratory Hypersensitivity

10/2023	Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes.
7/2017	Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.
1/2017	KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma.
4/2014	Variability of methacholine bronchoprovocation and the effect of inhaled corticosteroids in mild asthma.
7/2012	Methacholine challenge test: diagnostic characteristics in asthmatic patients receiving controller medications.
10/2010	A trial of clarithromycin for the treatment of suboptimally controlled asthma.

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Mario Castro Research Topics

Disease

208	Asthma (Bronchial Asthma) 05/2024 - 04/2004
45	Inflammation (Inflammations) 04/2024 - 04/2004
13	Bronchiolitis 01/2024 - 01/2005
11	COVID-19 11/2023 - 01/2021
9	Eosinophilia 04/2024 - 08/2009
8	Respiratory Sounds (Crackle) 01/2024 - 01/2005
7	Pneumonia (Pneumonitis) 11/2023 - 08/2011
7	Infections 09/2023 - 01/2005
6	Airway Remodeling 01/2024 - 09/2009
6	Respiratory Hypersensitivity 10/2023 - 10/2010
6	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 01/2012
6	Chronic Obstructive Pulmonary Disease (COPD) 01/2018 - 10/2010
5	Virus Diseases (Viral Diseases) 01/2021 - 08/2006
5	Lung Diseases (Lung Disease) 01/2018 - 01/2005
4	Obesity 01/2023 - 06/2011
4	Airway Obstruction (Choking) 01/2020 - 07/2007
4	Nasopharyngitis 01/2020 - 11/2011
3	Hypersensitivity (Allergy) 01/2021 - 08/2009
3	Body Weight (Weight, Body) 01/2019 - 05/2015
3	Injection Site Reaction 01/2018 - 11/2014
3	Pain (Aches) 11/2011 - 08/2008
2	Disease Progression 11/2023 - 08/2006
2	Rhinosinusitis 10/2023 - 01/2020
2	Nasal Polyps (Nasal Polyp) 10/2023 - 05/2014
2	Neoplasms (Cancer) 11/2021 - 12/2010
2	Hypertension (High Blood Pressure) 01/2021 - 01/2016
2	Anaphylaxis (Anaphylactic Shock) 01/2020 - 05/2015

Drug/Important Bio-Agent (IBA)

77	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023 - 04/2004
39	Biomarkers (Surrogate Marker)IBA 05/2024 - 05/2010
21	dupilumabIBA 02/2024 - 07/2016
21	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2024 - 02/2007
21	Bronchodilator Agents (Bronchodilators)IBA 10/2023 - 01/2005
18	Immunoglobulin E (IgE)IBA 11/2023 - 01/2007
12	Interleukin-13IBA 01/2021 - 02/2006
10	CytokinesIBA 01/2024 - 01/2008
10	Fluticasone (Cutivate)FDA LinkGeneric 12/2021 - 04/2004
9	Proteins (Proteins, Gene)FDA Link 05/2024 - 09/2008
9	Interleukin-5 (Interleukin 5)IBA 01/2024 - 01/2007
9	GlucocorticoidsIBA 09/2023 - 04/2004
9	Monoclonal AntibodiesIBA 01/2022 - 11/2014
9	SteroidsIBA 01/2022 - 04/2004
9	Methacholine Chloride (Methacholine)FDA Link 01/2017 - 01/2008
8	Interleukin-4 (Interleukin 4)IBA 01/2024 - 10/2008
8	reslizumabIBA 01/2023 - 11/2011
7	Salmeterol Xinafoate (Serevent)FDA Link 06/2023 - 05/2007
7	AllergensIBA 01/2021 - 04/2004
6	Azithromycin (Zithromax)FDA LinkGeneric 01/2024 - 05/2015
6	Vitamin D FDA LinkGeneric 10/2018 - 05/2014
5	InterleukinsIBA 01/2024 - 08/2006
5	Tiotropium Bromide (Spiriva)FDA Link 01/2022 - 10/2010
5	Albuterol (Salbutamol)FDA LinkGeneric 11/2013 - 06/2008
4	Eosinophil PeroxidaseIBA 04/2024 - 11/2020
4	Messenger RNA (mRNA)IBA 10/2023 - 12/2014
4	VaccinesIBA 01/2023 - 02/2006
4	SmokeIBA 12/2021 - 01/2005
4	LigandsIBA 01/2021 - 11/2014
4	lipoxin A4IBA 01/2018 - 09/2008
4	montelukast (Singulair)FDA Link 12/2011 - 05/2007
3	mepolizumabIBA 04/2024 - 01/2019
3	ChemokinesIBA 01/2024 - 01/2023
3	Oxidants (Oxidizing Agents)IBA 12/2023 - 05/2011
3	Fluvoxamine (Luvox)FDA LinkGeneric 11/2023 - 11/2022
3	3- (2- (4- azidobenzamidino)ethyl)- 5- hydroxyindole (SABA)IBA 11/2023 - 05/2021
3	RNA (Ribonucleic Acid)IBA 06/2023 - 02/2011
3	benralizumabIBA 01/2023 - 11/2014
3	Ivermectin (Mectizan)FDA Link 01/2023 - 10/2022
3	Mometasone Furoate (Nasonex)FDA LinkGeneric 01/2022 - 03/2015
3	AndrogensIBA 01/2021 - 04/2018
3	InterferonsIBA 01/2021 - 12/2014
3	Triamcinolone (Aristocort)FDA Link 01/2021 - 01/2019
3	Antiviral Agents (Antivirals)IBA 01/2021 - 04/2004
3	16S Ribosomal RNAIBA 12/2020 - 07/2017
3	Interleukin-6 (Interleukin 6)IBA 10/2020 - 01/2016
3	MacrolidesIBA 01/2020 - 01/2007
3	anti-IgE antibodiesIBA 01/2020 - 01/2019
3	Cholecalciferol (Vitamin D3)FDA Link 10/2018 - 05/2014
3	Interleukin-33IBA 08/2013 - 07/2011
3	Arginine (L-Arginine)FDA Link 01/2013 - 10/2008
3	Influenza Vaccines (Influenza Vaccine)FDA Link 12/2006 - 04/2004
2	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 01/2019
2	NucleotidesIBA 04/2024 - 01/2013
2	Interleukin-2 (IL2)IBA 01/2024 - 10/2008
2	Interleukin-8 (Interleukin 8)IBA 01/2024 - 05/2015
2	Dihydrotachysterol (AT 10)IBA 12/2023 - 09/2012
2	Superoxide DismutaseIBA 12/2023 - 05/2011
2	LeukotrienesIBA 06/2023 - 09/2008
2	tezepelumabIBA 01/2023 - 01/2022
2	Omalizumab (Xolair)FDA Link 01/2023 - 01/2016
2	Formoterol Fumarate (Oxis)FDA Link 01/2023 - 01/2023
2	Muscarinic AntagonistsIBA 01/2022 - 01/2019
2	prostaglandin D2 receptorIBA 01/2022 - 05/2021
2	AntibodiesIBA 01/2022 - 10/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 01/2007
2	Interleukin-5 Receptors (Interleukin 5 Receptor)IBA 01/2020 - 11/2014

Therapy/Procedure

73	Therapeutics 01/2024 - 04/2004
23	Bronchial Thermoplasty 12/2023 - 01/2010
7	Precision Medicine 01/2021 - 01/2009
6	Nebulizers and Vaporizers (Inhaler) 01/2023 - 12/2011
4	Biological Therapy 05/2019 - 01/2016
2	Length of Stay 01/2021 - 01/2005